10 Best Luxury Wellness Resorts in Florida for 2025

Nestled along Florida’s stunning coastline, Eau Palm Beach Resort & Spa offers the ultimate luxury wellness experience. This Forbes Five-Star resort combines oceanfront elegance with exceptional spa amenities to create a rejuvenating escape from everyday life.

The resort features plush accommodations and two oceanfront pools where you can relax while enjoying the Atlantic breeze. Your wellness journey is enhanced by complimentary fitness classes and 24-hour access to their state-of-the-art fitness center.

The crown jewel of this property is undoubtedly their Five-Star spa. With their spa getaway package, you’ll receive a generous $500 credit to indulge in transformative treatments. You can also enjoy healthy cuisine at their spa terrace café, Savor, with an included $50 dining credit.

Beyond wellness, the resort offers multiple dining options and amenities including tennis courts and a tranquil water garden. Your experience begins with a welcome glass of champagne, setting the tone for a luxurious stay focused on relaxation and renewal.

Nestled on 22 acres of Tampa Bay waterfront, Safety Harbor Resort and Spa offers a perfect blend of historic charm and luxury wellness. The resort features traditional lodging with spacious, well-appointed guestrooms, most overlooking the sparkling waters of Tampa Bay.

At the heart of this destination is its impressive 50,000-square-foot spa and fitness center. You can indulge in a wide range of spa services designed for relaxation and rejuvenation while enjoying the natural surroundings of this historic wellness location.

Your dining options include the Fountain Grille restaurant, a waterfront tiki bar, and Tampa Bay’s best Sunday brunch. The resort’s central location puts you within walking distance of Safety Harbor’s quaint downtown with its shops, restaurants, and events.

You’ll appreciate the convenience of being close to two international airports and the famous white sands of Clearwater Beach, making this resort an accessible luxury escape in the heart of Tampa Bay.

Nestled along one of Miami Beach’s longest stretches of shoreline, Carillon Miami Wellness Resort offers a unique approach to wellness that balances luxury indulgence with comprehensive health services. You’ll find an impressive 70,000 square-foot wellness center where Western, Eastern, Alternative, and Aesthetic medicine combine to create customized treatment plans.

The accommodations feature spacious one and two-bedroom luxury apartments with breathtaking views of either the Atlantic Ocean or Miami skyline. Each apartment includes a separate living room, fully-equipped kitchen, and spa-like bathroom, providing all the comforts of home with the amenities of a resort.

For fitness enthusiasts, the resort offers a cutting-edge fitness center with ocean views, Technogym cardio and strength training equipment, and over 65 weekly fitness classes. You can take advantage of one-on-one instruction to elevate your workout routine or try the innovative wellness technologies like IV therapy and salt bath treatments.

The exclusive spa and beach club provides the perfect setting for relaxation, while four pools offer variety for your swimming pleasure. For a truly rejuvenating experience, the Sleep Well Retreat program features the innovative Bryte Balance™ Smart Bed along with sleep seminars, wellness treatments, and meditation sessions.

Nestled on the pristine shores of Atlantic Beach, One Ocean Resort & Spa offers a luxurious wellness escape just minutes from Jacksonville. This upscale destination combines elegant accommodations with personalized service, including dedicated butler attention for every guest.

The chic rooms and suites feature stunning ocean views that create an immediate sense of tranquility. You’ll appreciate the thoughtful design that seamlessly blends comfort with coastal sophistication, allowing you to fully unwind during your stay.

The resort’s spa facilities provide comprehensive wellness treatments designed to rejuvenate both body and mind. From signature massages to specialized skin therapies, the professional staff delivers exceptional care in a serene environment.

Dining at One Ocean emphasizes fresh, locally-sourced ingredients prepared with culinary expertise. You can enjoy upscale meals while gazing at Atlantic Ocean views, completing the sensory experience that makes this resort a standout wellness destination in Florida.

Nestled in the Florida Keys, Little Palm Island Resort & Spa offers an exclusive escape from the everyday world. This secluded luxury resort is accessible only by boat or seaplane, ensuring privacy and tranquility throughout your stay. The resort’s TV-free bungalows encourage you to disconnect and truly immerse yourself in the natural beauty surrounding you.

The wellness experience at Little Palm Island centers around its world-class SpaTerre, where you can indulge in treatments inspired by both Eastern and Western techniques. After your spa session, you can lounge on pristine sandy beaches or take a refreshing dip in the outdoor pool overlooking the Gulf of Mexico.

Accommodations feature thatched-roof bungalows with elegant tropical décor, private decks, and outdoor showers. Each space is designed to blend seamlessly with the island’s lush landscape while providing all the luxury amenities you expect from a five-star resort.

The culinary offerings emphasize fresh, locally-sourced ingredients with a focus on seafood. You can enjoy a romantic dinner on the beach or dine at the acclaimed restaurant with panoramic water views, completing your wellness journey with nourishing, expertly prepared cuisine.

Nestled within The Carillon Wellness Resort in Miami Beach, Best Life-ing offers custom luxury healing and wellness retreats designed to transform your mind, body, and spirit. Founded by Julia Brodska, author of the #1 international bestseller, this wellness center brings together healers, teachers, and coaches to create bespoke experiences.

Their private retreats are fully customizable to your specific goals and intentions. You can choose any location, duration, and focus area for your wellness journey. Best Life-ing specializes in creating personalized itineraries that blend relaxation with self-discovery.

The center features innovative wellness technologies like the RLX Satori Wellness Lounger, which uses Quantum Harmonics™ sound technology to promote deep relaxation. You can enhance your experience with additional holistic therapies such as Reiki, hypnotherapy, guided meditation, or breathwork.

Beyond multi-day retreats, Best Life-ing offers half-day and full-day mini retreats for those seeking shorter wellness experiences. They’ve also partnered with the biostation to provide enhanced biomedical wellness retreats that combine modern and traditional therapies.

Nestled along Fort Lauderdale’s Federal Highway, Thermae Retreat stands as a beacon of holistic wellness in South Florida’s luxury spa landscape. This health-conscious sanctuary specializes in holistic treatments that restore balance to both body and mind, using only organic vegan products throughout their services.

You’ll discover a comprehensive wellness experience offering everything from rejuvenating facials to therapeutic massage modalities including Thai and sports massage. Their Reiki therapy services provide energy healing that complements their more traditional bodywork offerings, creating a truly integrated approach to wellness.

The retreat environment has been thoughtfully designed to transport you away from everyday stresses. Their sauna facilities promote detoxification while their wellness programs encourage sustainable health practices that extend beyond your visit.

For those seeking authentic healing experiences rather than superficial pampering, Thermae Retreat delivers treatments rooted in traditional practices while incorporating modern wellness understanding. You’ll leave feeling renewed and equipped with knowledge to maintain your wellness journey.

The Spa in Seaside offers a sanctuary of relaxation nestled in the charming community of Seaside, Florida. You’ll find this wellness haven provides an exceptional escape from the ordinary, boasting a comprehensive menu of rejuvenating treatments.

The spa’s professional staff delivers personalized service, ensuring your wellness journey addresses your specific needs. Their expertise extends across various therapeutic techniques, from soothing massages to revitalizing facials and body treatments.

Located in Santa Rosa Beach, this premier day spa combines luxury with authentic care in a serene setting. You can expect attentive service that has earned the spa its stellar reputation among locals and visitors alike.

The thoughtfully designed environment creates a peaceful atmosphere where you can disconnect from stress and focus entirely on your wellbeing. Many guests particularly appreciate the attention to detail that enhances each treatment experience.

Costa d’Este Beach Resort & Spa offers a luxurious beachfront retreat in Vero Beach, owned by celebrities Gloria and Emilio Estefan. You can enjoy immediate beach access with the soothing sounds of crashing waves right outside your door.

The resort features 94 beautifully appointed rooms and suites, many offering spectacular Atlantic Ocean views. You’ll find accommodations ranging from cozy rooms to spacious suites and indulgent penthouse options, providing the perfect setting for your Florida getaway.

Your dining experience includes exquisite ocean-view options at The Wave Kitchen & Bar, featuring locally sourced organic produce and freshly caught seafood. For a more casual atmosphere, the beachside Cabana Bar offers refreshing drinks and meals with stunning views.

The wellness offerings at Costa d’Este are exceptional, with a fully equipped spa and fitness center. You can indulge in signature massages, facials, and body treatments at C|SPA, leaving you feeling refreshed and revitalized. When not pampering yourself, unwind at the oceanfront infinity pool or bask on golden sand beaches.

Nestled in the tranquil countryside of Alachua, Florida, Ayurveda Health Retreat offers a sanctuary dedicated to holistic healing through ancient Ayurvedic practices. This serene wellness destination provides personalized treatments designed to restore balance to your body, mind, and spirit.

The retreat has earned a perfect 5-star rating from guests who consistently praise its transformative effects. Visitors like Margaret from Florida have described feeling “reborn” after just five days of treatment, noting significant improvements in both physical and mental wellbeing.

You’ll find a comprehensive approach to wellness here with specialized massage therapy based on traditional Ayurvedic principles. The peaceful rural setting enhances your healing journey, creating the ideal environment to disconnect from daily stressors and focus entirely on your health renewal.

The experienced practitioners at Ayurveda Health Retreat create individualized treatment plans that address your specific health concerns, whether you’re seeking relief from chronic conditions or simply need rejuvenation from the demands of modern life.